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Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
Editors

Kristie SourialM. D.

Received January 14, 1998 by eDrugstore.com for Erectile Dysfunction medication. For additional information or to place an order, please eDrugstore.com.

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Cialis has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.

Common side effects reported from Cialis use include:

  • Headache
  • Indigestion
  • Heartburn
  • Upset stomach
  • Gas
  • Nausea
  • Flushing

More severe side effects include:

  • Painful erections or erections that last longer than 4 hours
  • Sudden loss of vision
  • Sudden loss of hearing
  • Ringing in the ears
  • Chest pain
  • Shortness of breath
  • Painful urination
  • Increased urination frequency
  • Fainting
  • Dizziness
  • Skin rash
  • Hives
  • Facial swelling

If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.

As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Cialis. Cialis can interact with bodily substances, causing potentially serious adverse reactions.

Specifically, you should inform your health care provider of any alpha-blocker, antifungal, HIV protease inhibitor, or high blood pressure medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.

In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.

Read More This Part IHow to Avoid The Most Common Side Effects of Cialis. Part I: Tips. Cialis is a prescription medication that can cause a serious side effect when taken at the same time every day. Take one tablet at a time. Cialis can cause a serious adverse reaction if you take it at the same time every day. Some people experience a side effect that goes away as your body gets used to the drug. Rarely, a side effect that does not go away is a rare side effect that could occur. Tell your health care provider if any of the following side effects are troublesome:
  • Headache that is more than 4 hours old
  • Heart palpitations
  • Swelling in the arms or legs
  • Severe stomach pain

As with all prescription medications, inform your doctor of any medical conditions you manage, as they can interact with certain medications and provide you with if you have.

In addition, let your doctor know if you are pregnant or plan to become pregnant. Cialis can cause potential birth defects in small children, so you should not take this medication if you are or will be taking other medications. Your doctor should discuss the benefits and risks of Cialis during treatment with Cialis.

In part one, you should also inform your doctor of any medical problems, such as heart problems, high blood pressure, or low blood pressure, that are causing you to feel light-headed, tired, or under the weather. This medication can cause a serious adverse reaction if you take it at the same time every day. Other rare side effects may include:

  • Zithromax
  • Trulicity
  • Pantoprazole
  • Vibramycin

As with all prescription medications, inform your doctor of any medical problems, such as a problem with your heart or a recent heart attack, or if you have a bleeding disorder.

In addition, let your doctor know if you have recently had a heart attack, or if you have ever had an heart attack or heart failure.

In part two, you should also let your doctor know if you have recently had a stroke, a heart attack, an irregular heartbeat, an heavy bleeding or blood clots, or if you have a liver or kidney problem.

Cialis has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.

Common side effects reported from Cialis use include:

  • Headache
  • Indigestion
  • Heartburn
  • Upset stomach
  • Gas
  • Nausea
  • Flushing

More severe side effects include:

  • Painful erections or erections that last longer than 4 hours
  • Sudden loss of vision
  • Sudden loss of hearing
  • Ringing in the ears
  • Chest pain
  • Shortness of breath
  • Painful urination
  • Increased urination frequency
  • Fainting
  • Dizziness
  • Skin rash
  • Hives
  • Facial swelling

If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.

As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Cialis. Cialis can interact with bodily substances, causing potentially serious adverse reactions.

Specifically, you should inform your health care provider of any alpha-blocker, antifungal, HIV protease inhibitor, or high blood pressure medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.

In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.

Show More Nov 2023 How do you manage Cialis side effects? Cialis does not produce an erection until after you have taken it. As a result, there is no guarantee that you will not be taken an erection when you take Cialis.Possible Side Effects Reducing Cialis can help keep you from recurring erectile dysfunction.

As with all prescription medications, inform your doctor of any and all medications, prescription drugs, and supplements you are taking.

Erectile dysfunction

Erectile dysfunction (ED) is a condition that occurs when a man cannot get or keep an erection during sexual activity. It can be caused by various factors, including age, underlying health conditions, stress, and other medications.

Before taking Cialis, tell your doctor if you have any of the following:

  • At least 10 consecutive Thyroid Testings
  • A personal or family history of ED
  • Any of the following conditions
  • Your body may be unable to produce cGMP for erections, resulting in ED
  • Your metabolism may be altered
  • You are taking a specific medication called for example, sildenafil for hypertension

iddicate the effects of sildenafil with an antacid blend containing an antacid blend containing an antacid blend containing an antacid blend containing an antacid blend containing an antacid blend containing an antacid blend containing an antacid blend containing an antacid blend containing an antacid blend containing an antacid blend containing an antacid blend containing an antacid blend for erectile dysfunction treatment.

The effects of Cialis can be decreased by a combination of the following ingredients:

  • sildenafil
  • tadalafil
  • vardenafil

Ask your pharmacist about the combination element that can reduce the effectiveness of Cialis.

iddicate the combination by carefully considering all the following factors:

  • How much Cialis can be taken?
  • How long you plan to take Cialis
  • Where you take your medication, how you use it, and how much you use it

Ask your pharmacist for advice about using Cialis safely.

Cialis has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.

Common side effects reported from Cialis use include:

  • Headache
  • Indigestion
  • Heartburn
  • Upset stomach
  • Gas
  • Nausea
  • Flushing

More severe side effects include:

  • Painful erections or erections that last longer than 4 hours
  • Sudden loss of vision
  • Sudden loss of hearing
  • Ringing in the ears
  • Chest pain
  • Shortness of breath
  • Painful urination
  • Increased urination frequency
  • Fainting
  • Dizziness
  • Skin rash
  • Hives
  • Facial swelling

If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.

As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Cialis. Cialis can interact with bodily substances, causing potentially serious adverse reactions.

Specifically, you should inform your health care provider of any alpha-blocker, antifungal, HIV protease inhibitor, or high blood pressure medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.

In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.

Read more about Cialis's effects and possible side effects.Learn more about the side effects of Cialis and how to reduce them (keepers) can get started with a free heartburn medication program

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